A new report by some researchers from Israel states that they managed to invent the very first completely personalized tissue implant, which was engineered from a patient’s own cells and materials. This new type of technology means that it’s possible to create any kind of tissue implant, all the way from the spinal cord, to the brain or heart, just by using a small fatty tissue biopsy.
The lead researcher Professor Tal Dvir, of the Tel Aviv University Center for Nanoscience and Nanotechnology and Sagol Center for Regenerative Biotechnology said that the research team managed to create a new, personalized hydrogel, all thanks to materials they got during a biopsy, which helped them differentiate the fatty tissue cells from the different cell types. They can then use this information to be able to make spinal cord, cardiac, cortical, and plenty of other types of tissue implants that can treat various diseases. And since the material as well as the cells that are being used, come from the patients themselves, it means that none of the implants can provoke an immune response. This, in turn, is going to ensure that the defected organ maintains proper regeneration.
The entire research team was comprised by the lead researcher, Professor Tal Dvir, his postdoctoral researcher Reuven Ediri, two doctoral students, Nadav Noor, and Idan Gal, and in collaboration with Professors Dan Peer and Irit Gat Viks, from Tel Aviv University’s Department of Cell Research and Immunology, as well as Professor Lior Heller of Assaf HaRofeh Medical Center in Israel.
Right now, with the tissue engineering that ’s used in regenerative medicine, the cells are isolated from a patient and then cultured in biomaterials, so the scientists can assemble a functional tissue. And after the transplantation, it’s possible for them to induce an immune response which leads to rejection of the new tissue because the biomaterials being used can be synthetic or natural. But with this new technology, scientists can engineer any tissue, which won’t be rejected by the patient’s body, since they are made from the patient's own cells, and there is going to be a minimal risk of having an immune response.